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EAAT2 activator 1

CAS No. 892415-28-0

EAAT2 activator 1( F2005-0304 | 3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine )

Catalog No. M28620 CAS No. 892415-28-0

F2005-0304 is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    EAAT2 activator 1
  • Note
    Research use only, not for human use.
  • Brief Description
    F2005-0304 is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.
  • Description
    F2005-0304 is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    F2005-0304 | 3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    BD1-BRD4|BRD4-BD2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    892415-28-0
  • Formula Weight
    331.8
  • Molecular Formula
    C16H11ClFN3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (75.35 mM)
  • SMILES
    Fc1cccc(Cl)c1CSc(cc1)nnc1-c1ncccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211.
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